Description
Human TP53BP2 Recombinant Protein (N-His)
Human TP53BP2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val922-Ala1128, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Apoptosis-stimulating of p53 protein 2 is a ~125 kDa protein. Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53. For research use only.
Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of NAE1 to conjugate NEDD8 to CUL1, and thereby decreases NAE1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
| Product Name: | Human TP53BP2 Recombinant Protein (N-His) |
| SKU: | GXRP13763 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 53BP2, ASPP2, Apoptosis-stimulating of p53 protein 2, BBP, Bbp, Bcl2-binding protein, Renal carcinoma antigen NY-REN-51, TP53BP2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val922-Ala1128 |
| UniProt: | Q13625 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
