Description
Human TP63 Recombinant Protein (N-His)
Human TP63 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser41-Cys339, with an N-terminal His tag. Predicted molecular weight: 35.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tumor protein 63 (TP63/p40) is a ~76 kDa protein. Acts as a sequence specific DNA binding transcriptional activator or repressor. For research use only.
The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2.
| Product Name: | Human TP63 Recombinant Protein (N-His) |
| SKU: | GXRP02856 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Keratinocyte transcription factor KET, P63, KET, Tumor protein p73-like, p63, P73L, CUSP, P73H, p40, Tumor protein 63, TP73L, Transformation-related protein 63, TP63, Chronic ulcerative stomatitis protein, p73L, p51 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser41-Cys339 |
| Calculated MW: | 35.54 kDa |
| UniProt: | Q9H3D4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
