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Human TRABD2A Recombinant Protein (N-His)
Key Features

Human TRABD2A Recombinant Protein (N-His) (GXRP13066)

SKU GXRP13066
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human TRABD2A Recombinant Protein (N-His)

Human TRABD2A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala20-His360, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Metalloprotease TIKI1 is a ~57 kDa protein. Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. For research use only.

Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

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