Description
Human TRIM16 Recombinant Protein (N-His)
Human TRIM16 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys384-Pro564, with an N-terminal His tag. Predicted molecular weight: 23.26 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tripartite motif-containing protein 16 (TRIM16) is a ~63 kDa protein. E3 ubiquitin ligase that plays an essential role in the organization of autophagic response and ubiquitination upon lysosomal and phagosomal damages. For research use only.
Plays a role in the stress-induced biogenesis and degradation of protein aggresomes by regulating the p62-KEAP1-NRF2 signaling and particularly by modulating the ubiquitination levels and thus stability of NRF2. Acts as a scaffold protein and facilitates autophagic degradation of protein aggregates by interacting with p62/SQSTM, ATG16L1 and LC3B/MAP1LC3B. In turn, protects the cell against oxidative stress-induced cell death as a consequence of endomembrane damage.
| Product Name: | Human TRIM16 Recombinant Protein (N-His) |
| SKU: | GXRP04625 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Estrogen-responsive B box protein, Tripartite motif-containing protein 16, TRIM16, EBBP, E3 ubiquitin-protein ligase TRIM16 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys384-Pro564 |
| Calculated MW: | 23.26 kDa |
| UniProt: | O95361 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
