Description
Human TRIM40 Recombinant Protein (N-His)
Human TRIM40 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu258, with an N-terminal His tag. Predicted molecular weight: 31.50 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin ligase TRIM40 is a ~29 kDa protein. E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response. For research use only.
Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation. Also promotes the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation.
| Product Name: | Human TRIM40 Recombinant Protein (N-His) |
| SKU: | GXRP09461 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | E3 ubiquitin ligase TRIM40; 2.3.2.27; Probable E3 NEDD8-protein ligase; RING finger protein 35; TRIM40; RNF35 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu258 |
| Calculated MW: | 31.50 kDa |
| UniProt: | Q6P9F5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
