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Human TRIP11 Recombinant Protein (N-His)
Key Features

Human TRIP11 Recombinant Protein (N-His) (GXRP06341)

SKU GXRP06341
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human TRIP11 Recombinant Protein (N-His)

Human TRIP11 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln14-Tyr148, with an N-terminal His tag. Predicted molecular weight: 17.09 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thyroid receptor-interacting protein 11 (TRIP11) is a ~227 kDa protein. Is a membrane tether required for vesicle tethering to Golgi. For research use only.

Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription.

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