Description
Human TXNIP Recombinant Protein (N-His)
Human TXNIP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile32-Ala367, with an N-terminal His tag. Predicted molecular weight: 39.68 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Thioredoxin-interacting protein (TXNIP) is a ~43 kDa protein. May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. For research use only.
Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
| Product Name: | Human TXNIP Recombinant Protein (N-His) |
| SKU: | GXRP02857 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | VDUP1, Vitamin D3 up-regulated protein 1, TXNIP, Thioredoxin-binding protein 2, Thioredoxin-interacting protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile32-Ala367 |
| Calculated MW: | 39.68 kDa |
| UniProt: | Q9H3M7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
