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Human UBE2N Recombinant Protein (N-His)
Key Features

Human UBE2N Recombinant Protein (N-His) (GXRP09408)

SKU GXRP09408
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human UBE2N Recombinant Protein (N-His)

Human UBE2N Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ile152, with an N-terminal His tag. Predicted molecular weight: 19.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquitin-conjugating enzyme E2 N is a ~17 kDa protein. The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. For research use only.

This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

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