Description
Human UCHL3 Recombinant Protein (N-His)
Human UCHL3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ala230, with an N-terminal His tag. Predicted molecular weight: 28.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) is a ~26 kDa protein. Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. For research use only.
Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3'', and exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis.
| Product Name: | Human UCHL3 Recombinant Protein (N-His) |
| SKU: | GXRP05664 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | UCH-L3, Ubiquitin thioesterase L3, UCHL3, Ubiquitin carboxyl-terminal hydrolase isozyme L3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ala230 |
| Calculated MW: | 28.35 kDa |
| UniProt: | P15374 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
