Human UCHL3/UCH-L3 Recombinant Protein (RPES1881)
- SKU:
- RPES1881
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Frequently bought together:
Description
system_update_altDatasheet
Human UCHL3/UCH-L3 Recombinant Protein
Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.
| Product Name: | Human UCHL3/UCH-L3 Recombinant Protein (RPES1881) |
| Product Code: | RPES1881 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3, UCH-L3, Ubiquitin Thioesterase L3, UCHL3 |
| Accession: | P15374 |
| Sequence: | Met 1-Ala230 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3 is produced by our E.coli expression system and the target gene encoding Met1-Ala230 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 27.3 kDa |
| AP Mol Mass: | 25 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 50mM TrisHCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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