Description
Human UPB1 Recombinant Protein (N-His)
Human UPB1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Trp121-Glu384, with an N-terminal His tag. Predicted molecular weight: 31.9 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-ureidopropionase (UPB1) is a ~43 kDa protein. Catalyzes a late step in pyrimidine degradation. For research use only.
Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). 1. van Kuilenburg, AB. et al. (2012) Biochimica et biophysica acta 1822, 1096-108. PMID: 22525402 2. Nakajima, Y. et al. (2014) Journal of inherited metabolic disease 37, 801-12. PMID: 24526388 3. Van Kuilenburg, AB. et al. (1999) Analytical biochemistry 272, 250-3. PMID: 10415095 4. Vreken, P. et al. (1999) Biochimica et biophysica acta 1447, 251-7. PMID: 10542323 5. Sakamoto, T. et al. (2001) Journal of nutritional science and vitaminology 47, 132-8. PMID: 11508704 6. Maurer, D. et al. (2018) The Biochemical journal 475, 2395-2416. PMID: 29976570
| Product Name: | Human UPB1 Recombinant Protein (N-His) |
| SKU: | GXRP03001 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | UPB1, N-carbamoyl-beta-alanine amidohydrolase, Beta-ureidopropionase, Beta-alanine synthase, BUP1, BUP-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Trp121-Glu384 |
| Calculated MW: | 31.9 kDa |
| UniProt: | Q9UBR1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
