Description
Human UQCR11 Recombinant Protein (N-GST)
Human UQCR11 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Met1-Asn56, with an N-terminal GST tag. Predicted molecular weight: 33.39 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cytochrome b-c1 complex subunit 10 (UQCR11) is a ~6 kDa protein. Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. For research use only.
The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. QCR10 has a role in CIII assembly and RIP1 stability.
| Product Name: | Human UQCR11 Recombinant Protein (N-GST) |
| SKU: | GXRP06768 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | UQCR, Complex III subunit 10, Complex III subunit XI, Cytochrome b-c1 complex subunit 10, UQCR11, Ubiquinol-cytochrome c reductase complex 6.4 kDa protein |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asn56 |
| Calculated MW: | 33.39 kDa |
| UniProt: | O14957 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
