Description
Human USP21 Recombinant Protein (N-His)
Human USP21 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr220-Leu565, with an N-terminal His tag. Predicted molecular weight: 41.45 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ubiquitin carboxyl-terminal hydrolase 21 (USP21) is a ~62 kDa protein. Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. For research use only.
Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Deubiquitinates BAZ2A/TIP5 leading to its stabilization. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
| Product Name: | Human USP21 Recombinant Protein (N-His) |
| SKU: | GXRP04601 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin thioesterase 21, Deubiquitinating enzyme 21, USP21, Ubiquitin-specific-processing protease 21, USP23 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr220-Leu565 |
| Calculated MW: | 41.45 kDa |
| UniProt: | Q9UK80 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
