Description
Human UVRAG Recombinant Protein (N-His)
Human UVRAG Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg41-Ala164, with an N-terminal His tag. Predicted molecular weight: 16.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. UV radiation resistance-associated gene protein (UVRAG) is a ~78 kDa protein. Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. For research use only.
Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex; the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P). During autophagy acts as a regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturation of autophagosomes and endocytosis. Activates lipid kinase activity of PIK3C3. Involved in the regulation of degradative endocytic trafficking and cytokinesis, and in regulation of ATG9A transport from the Golgi to the autophagosome; the functions seems to implicate its association with PI3KC3-C2.
| Product Name: | Human UVRAG Recombinant Protein (N-His) |
| SKU: | GXRP06426 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | UV radiation resistance-associated gene protein, p63, UVRAG |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg41-Ala164 |
| Calculated MW: | 16.85 kDa |
| UniProt: | Q9P2Y5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
