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Human VPS25 Recombinant Protein (N-His)
Key Features

Human VPS25 Recombinant Protein (N-His) (GXRP13890)

SKU GXRP13890
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human VPS25 Recombinant Protein (N-His)

Human VPS25 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Phe176, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Vacuolar protein-sorting-associated protein 25 is a ~20 kDa protein. Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. For research use only.

The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.

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