Description
Human VPS39 Recombinant Protein (N-His)
Human VPS39 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Val309, with an N-terminal His tag. Predicted molecular weight: 37.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Vam6/Vps39-like protein is a ~101 kDa protein. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. For research use only.
Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.
| Product Name: | Human VPS39 Recombinant Protein (N-His) |
| SKU: | GXRP11430 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0770, TLP, TRAP1-like protein, VAM6, VPS39, Vam6/Vps39-like protein, hVam6p |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Val309 |
| Calculated MW: | 37.33 kDa |
| UniProt: | Q96JC1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
