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Human VWF Recombinant Protein (N-His)
Key Features

Human VWF Recombinant Protein (N-His) (GXRP00548)

SKU GXRP00548
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Human VWF Recombinant Protein (N-His)

Human VWF Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala23-Lys219, with an N-terminal His tag. Predicted molecular weight: 23.89 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. von Willebrand factor (VWF) is a ~309 kDa protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. For research use only.

Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

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