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Anti-IL36G Antibody (CAB8304)

SKU:
CAB8304
Product Type:
Antibody
Applications:
WB
IHC
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • Immunology Antibodies 3 Anti-IL36G Antibody CAB8304
  • Immunology Antibodies 3 Anti-IL36G Antibody CAB8304
  • Immunology Antibodies 3 Anti-IL36G Antibody CAB8304
€139 - €419
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Description

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Antibody Name:IL36G Rabbit Polyclonal Antibody
Antibody SKU:CAB8304
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human IL36G (NP_062564.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human IL36G (NP_062564.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRGT PGDA DGGG RAVY QSMC KPIT GTIN DLNQ QVWT LQGQ NLVA VPRS DSVT PVTV AVIT CKYP EALE QGRG DPIY LGIQ NPEM CLYC EKVG EQPT LQLK EQKI MDLY GQPE PVKP FLFY RAKT GRTS TLES VAFP DWFI ASSK RDQP IILT SELG KSYN TAFE LNIN D
Gene ID:56300
Uniprot:Q9NZH8
Cellular Location:Secreted
Calculated MW:14kDa/18kDa
Observed MW:Refer to figures
Synonyms:IL36G, IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1, IL1RP2
Background:The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Il1f9: Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytokine

Chromosomal Location of Human Ortholog: 2q12-q21

Cellular Component: extracellular space

Molecular Function:interleukin-1 receptor binding; cytokine activity

Biological Process: cell-cell signaling; cytokine and chemokine mediated signaling pathway; innate immune response; positive regulation of interleukin-6 production; negative regulation of myoblast differentiation; inflammatory response

NCBI Summary:The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
UniProt Code:Q9NZH8
NCBI GenInfo Identifier:25008596
NCBI Gene ID:56300
NCBI Accession:Q9NZH8.1
UniProt Secondary Accession:Q9NZH8,Q56B91, Q6UVX7, Q7RTZ9,
UniProt Related Accession:Q9NZH8
Molecular Weight:18,721 Da
NCBI Full Name:Interleukin-36 gamma
NCBI Synonym Full Names:interleukin 36, gamma
NCBI Official Symbol:IL36G  
NCBI Official Synonym Symbols:IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2  
NCBI Protein Information:interleukin-36 gamma; IL-1 epsilon; IL-1-epsilon; IL-1(EPSILON); interleukin-1 epsilon; IL-1 related protein 2; IL-1-related protein 2; interleukin-1 homolog 1; interleukin-1 family member 9; interleukin 1 family, member 9; interleukin 1-related protein 2
UniProt Protein Name:Interleukin-36 gamma
UniProt Synonym Protein Names:IL-1-related protein 2; IL-1RP2; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 9; IL-1F9; Interleukin-1 homolog 1
Protein Family:Interleukin
UniProt Gene Name:IL36G  
UniProt Entry Name:IL36G_HUMAN
Anti-IL36G Polyclonal Antibody (CAB8304)Immunohistochemistry of paraffin-embedded rat lung using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens).
Anti-IL36G Polyclonal Antibody (CAB8304)Immunohistochemistry of paraffin-embedded human esophagus using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens).
Anti-IL36G Polyclonal Antibody (CAB8304)Immunohistochemistry of paraffin-embedded mouse lung using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens).

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