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Integrin alpha 5 (ITGA5/CD49e) Polyclonal Antibody (CAB22018)

SKU:
CAB22018
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Integrin alpha 5 (ITGA5/CD49e) Polyclonal Antibody
SKU:CAB22018
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 42-995 of human Integrin alpha 5 (ITGA5/CD49e) (NP_002196.4).
Sequence:FNLD AEAP AVLS GPPG SFFG FSVE FYRP GTDG VSVL VGAP KANT SQPG VLQG GAVY LCPW GASP TQCT PIEF DSKG SRLL ESSL SSSE GEEP VEYK SLQW FGAT VRAH GSSI LACA PLYS WRTE KEPL SDPV GTCY LSTD NFTR ILEY APCR SDFS WAAG QGYC QGGF SAEF TKTG RVVL GGPG SYFW QGQI LSAT QEQI AESY YPEY LINL VQGQ LQTR QASS IYDD SYLG YSVA VGEF SGDD TEDF VAGV PKGN LTYG YVTI LNGS DIRS LYNF SGEQ MASY FGYA VAAT DVNG DGLD DLLV GAPL LMDR TPDG RPQE VGRV YVYL QHPA GIEP TPTL TLTG HDEF GRFG SSLT PLGD LDQD GYND VAIG APFG GETQ QGVV FVFP GGPG GLGS KPSQ VLQP LWAA SHTP DFFG SALR GGRD LDGN GYPD LIVG SFGV DKAV VYRG RPIV SASA SLTI FPAM FNPE ERSC SLEG NPVA CINL SFCL NASG KHVA DSIG FTVE LQLD WQKQ KGGV RRAL FLAS RQAT LTQT LLIQ NGAR EDCR EMKI YLRN ESEF RDKL SPIH IALN FSLD PQAP VDSH GLRP ALHY QSKS RIED KAQI LLDC GEDN ICVP DLQL EVFG EQNH VYLG DKNA LNLT FHAQ NVGE GGAY EAEL RVTA PPEA EYSG LVRH PGNF SSLS CDYF AVNQ SRLL VCDL GNPM KAGA SLWG GLRF TVPH LRDT KKTI QFDF QILS KNLN NSQS DVVS FRLS VEAQ AQVT LNGV SKPE AVLF PVSD WHPR DQPQ KEED LGPA VHHV YELI NQGP SSIS QGVL ELSC PQAL EGQQ LLYV TRVT GLNC TTNH PINP KGLE LDPE GSLH HQQK REAP SRSS ASSG PQIL KCPE AECF RLRC ELGP LHQQ ESQS LQLH FRVW AKTF LQRE HQPF SLQC EAVY KALK MPYR ILPR QLPQ KERQ VATA VQWT KAEG SY
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FNRA; CD49e; VLA-5; VLA5A; Integrin alpha 5 (ITGA5/CD49e)
Positive Sample:A-549,HeLa,NIH/3T3,C2C12
Conjugate:Unconjugated
Cellular Localization:cytoplasmic vesicle, endoplasmic reticulum, external side of plasma membrane, glutamatergic synapse, Golgi apparatus, plasma membrane, postsynaptic membrane
Calculated MW:115kDa
Observed MW:150kDa

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Purification Method:Affinity purification
Gene ID:3678
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Integrin alpha 5 (ITGA5/CD49e) antibody (CAB22018) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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