The INTS11 Monoclonal Antibody (CAB22698) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated by hybridoma technology, specifically targets the INTS11 protein in human samples and is validated for use in various experimental applications, including immunofluorescence and flow cytometry.INTS11 plays a crucial role in the regulation of gene expression, making it an important target for research in areas such as developmental biology, cancer biology, and neurobiology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
INTS11 Monoclonal Antibody
SKU:
CAB22698
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC58804
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:2000 - 1:7000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
Purification Method
Affinity purification
Gene ID
54973
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using INTS11 Rabbit mAb (CAB22698) at 1:6000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
