The KLK15 Antibody (CAB2757) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blot applications.Kallikrein 15, also known as PRSS9, is a serine protease that plays a significant role in proteolytic cascades, particularly in the kallikrein-kinin system. Its dysregulation has been linked to various diseases including cancer, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
KLK15 Antibody
SKU:
CAB2757
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ACO, HSRNASPH, KLK15
Positive Sample:
Mouse kidney, Rat kidney
Cellular Localization:
Secreted.
Calculated MW:
28kDa
Observed MW:
28kDa
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method
Affinity purification
Gene ID
55554
RRID
AB_2764603
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KLK15 Rabbit pAb (CAB2757) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
