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Immunology Antibodies 3 Anti-KDM4A Antibody CAB9267
Key Features

KDM4A Rabbit Monoclonal Antibody (CAB9267)

Datasheet MSDS
SKU CAB9267
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms JMJD2, JHDM3A, JMJD2A, TDRD14A, KDM4A
Research Use Immunology
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

KDM4A Monoclonal Antibody (CAB9267)

The KDM4A Monoclonal Antibody (CAB9267) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for immunohistochemistry and immunofluorescence applications.KDM4A, also known as Jumonji domain-containing protein 2A, plays a crucial role in histone demethylation and transcriptional regulation. Dysregulation of KDM4A has been linked to various diseases, including cancer, neurodevelopmental disorders, and metabolic diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:KDM4A Monoclonal Antibody
SKU:CAB9267
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC1503
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:GDGR VTVG EPCT RKKG SAAR SFSE RELA EVAD EYMF SLEE NKKS KGRR QPLS KLPR HHPL VLQE CVSD DETS EQLT PEEE AEET EAWA KPLS QLWQ NRPP N
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:JMJD2, JHDM3A, JMJD2A, TDRD14A, KDM4A
Positive Sample:HeLa, NIH/3T3, SH-SY5Y
Cellular Localization:Nucleus.
Calculated MW:121kDa
Observed MW:150kDa

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Purification MethodAffinity purification
Gene ID9682
RRIDAB_2863701
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using KDM4A Rabbit mAb (CAB9267) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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