The GBP2 Polyclonal Antibody (CAB19874) is a valuable tool for researchers studying GBP2, a guanylate-binding protein involved in immune responses to viral infections. This rabbit polyclonal antibody is highly specific to human samples and has been rigorously validated for use in Western blotting applications.GBP2 is a key player in the innate immune response, functioning to restrict viral replication and activate the immune system. By binding to GBP2, this antibody enables precise detection and analysis of the protein in a variety of cell types.
Its reliability and sensitivity make it an ideal choice for studies focusing on antiviral immune mechanisms and host-pathogen interactions.With its ability to target GBP2, this antibody is essential for unraveling the intricate molecular pathways involved in viral immunity. Researchers can utilize this tool to deepen their understanding of how GBP2 functions in immune defense, potentially leading to advancements in antiviral therapeutics and vaccine development.
Product Name:
[KO Validated] GBP2 Rabbit Polyclonal Antibody
SKU:
CAB19874
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2).
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.
Purification Method:
Affinity purification
Gene ID:
2634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and GBP2 knockout (KO) A-549 cells, using [KO Validated] GBP2 Rabbit pAb (CAB19874) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
