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[KO Validated] GBP2 Rabbit Polyclonal Antibody (CAB19874)

SKU:
CAB19874
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
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Description

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Product Name:[KO Validated] GBP2 Rabbit Polyclonal Antibody
SKU:CAB19874
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2).
Sequence:QDIF GPLE EDVK QGTF SKPG GYRL FTQK LQEL KNKY YQVP RKGI QAKE VLKK YLES KEDV ADAL LQTD QSLS EKEK AIEV ERIK AESA EAAK KMLE EIQK KNEE MMEQ KEK
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:GBP2; P2
Positive Sample:A-549
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Golgi apparatus membrane, Lipid-anchor, Membrane, perinuclear region.
Calculated MW:67kDa
Observed MW:67kDa

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.

Purification Method:Affinity purification
Gene ID:2634
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and GBP2 knockout (KO) A-549 cells, using [KO Validated] GBP2 Rabbit pAb (CAB19874) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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