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[KO Validated] hnRNP A1 Rabbit Polyclonal Antibody (CAB18094)

SKU:
CAB18094
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

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Product Name:[KO Validated] hnRNP A1 Rabbit Polyclonal Antibody
SKU:CAB18094
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human hnRNP A1 (NP_002127.1).
Sequence:MSKS ESPK EPEQ LRKL FIGG LSFE TTDE SLRS HFEQ WGTL TDCV VMRD PNTK RSRG FGFV TYAT VEEV DAAM NARP HKVD GRVV EPKR AVSR EDSQ RPGA HLTV KKIF VGGI KEDT EEHH LRDY FEQY GKIE VIEI MTDR
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:UP 1; ALS19; ALS20; HNRPA1; IBMPFD3; HNRPA1L3; hnRNP A1; hnRNP-A1; A1
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:39kDa
Observed MW:39kDa

This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Purification Method:Affinity purification
Gene ID:3178
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and hnRNP A1 knockout (KO) 293T cells, using [KO Validated] hnRNP A1 Rabbit pAb (CAB18094) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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