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[KO Validated] MyD88 Rabbit Monoclonal Antibody (CAB19082)

SKU:
CAB19082
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • KO Validated Antibodies 2 Anti-MyD88 Antibody KO Validated CAB19082
  • KO Validated Antibodies 2 Anti-MyD88 Antibody KO Validated CAB19082
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] MyD88 Rabbit Monoclonal Antibody
SKU:CAB19082
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MyD88 (NP_002459.3).
Sequence:LAEE MDFE YLEI RQLE TQAD PTGR LLDA WQGR PGAS VGRL LELL TKLG RDDV LLEL GPSI EEDC QKYI LKQQ QEEA EKPL QVAA VDSS VPRT AELA GITT L
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:WM1; IMD68; MYD88D; 88
Positive Sample:HeLa,A549
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:15kDa/20kDa/28kDa/31kDa/33kDa/34kDa
Observed MW:33kDa

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:4615
Clone Number:ARC52507
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and MyD88 knockout (KO) HeLa cells, using [KO Validated] MyD88 Rabbit mAb (CAB19082) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.

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