The KRT73 Antibody (PAC037482) is a polyclonal antibody specifically designed for research involving Keratin 73 (KRT73), a protein involved in the cytoskeleton of epithelial cells and hair follicles. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.KRT73 is a keratin protein that plays a crucial role in maintaining the structural integrity of epithelial tissues and hair follicles. Research has shown its involvement in hair growth and skin health, making it a target of interest in studies related to dermatology and hair biology.
The KRT73 Antibody binds specifically to the KRT73 protein, allowing for its detection and analysis in a variety of cell types.Understanding the function and regulation of KRT73 can provide valuable insights into the mechanisms underlying hair growth disorders, skin diseases, and other conditions affecting epithelial tissues. By using the KRT73 Antibody in research, scientists can gain a better understanding of the role of KRT73 in these processes and potentially identify new therapeutic targets for related disorders.
Antibody Name:
KRT73 Antibody (PACO37482)
Antibody SKU:
PACO37482
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin, type II cytoskeletal 73 protein (1-300AA)
Western blot. All lanes: KRT73 antibody at 4µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 59, 42 kDa. Observed band size: 59, 42 kDa.
Background:
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).
Synonyms:
Keratin, type II cytoskeletal 73 (Cytokeratin-73) (CK-73) (Keratin-73) (K73) (Type II inner root sheath-specific keratin-K6irs3) (Type-II keratin Kb36), KRT73, K6IRS3 KB36 KRT6IRS3
UniProt Protein Function:
K6IRS3: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 12q13.3Cellular Component: nucleusMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
