The LAMTOR1 Polyclonal Antibody (CAB21557) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.LAMTOR1, also known as p18, is crucial for the proper functioning of the Ragulator complex, which regulates the activity of the mTORC1 signaling pathway. Dysregulation of this pathway has been linked to various diseases, including cancer, metabolic disorders, and neurodegenerative conditions.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
LAMTOR1 Polyclonal Antibody
SKU:
CAB21557
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Membrane, Cytoplasmic Side, Late Endosome Membrane, Lipid-Anchor, Lysosome Membrane.
Calculated MW:
18kDa
Observed MW:
Refertofigures
Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex.
Purification Method
Affinity purification
Gene ID
55004
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LAMTOR1 Rabbit pAb (CAB21557) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
Confocal immunofluorescence analysis of U2OS cells using LAMTOR1 Rabbit pAb (CAB21557) at dilution of 1:100. Blue: DAPI for nuclear staining.
