The LINGO1 Antibody (CAB9369) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By selectively binding to the LINGO1 protein, this antibody enables researchers to detect and analyze LINGO1 expression in various cell types, making it an excellent choice for studies in neuroscience and neurology.LINGO1, a key regulator of neuronal growth and myelination, plays a crucial role in shaping the structure and function of the nervous system.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
LINGO1 Antibody
SKU:
CAB9369
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LERN1, MRT64, LRRN6A, UNQ201, LINGO1
Positive Sample:
MCF7, A-549, K-562, Mouse testis, Mouse lung
Cellular Localization:
Cell Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
70kDa
Observed MW:
70kDa
Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within generation of neurons and protein kinase B signaling. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. Implicated in autosomal recessive non-syndromic intellectual disability and glaucoma.
Purification Method
Affinity purification
Gene ID
84894
RRID
AB_2770190
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using LINGO1 Rabbit pAb (CAB9369) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
