The LSM12 Antibody (CAB15947) is a high-quality antibody developed for reliable detection and analysis of target proteins. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LSM12 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component for studies in molecular biology and gene expression.LSM12 is a vital component of the spliceosome complex, which plays a crucial role in RNA splicing and processing. Dysregulation of LSM12 has been linked to various diseases, including cancer and neurological disorders, making it a promising target for further research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
LSM12 Antibody
SKU:
CAB15947
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PNAS-135, LSM12
Positive Sample:
LO2, Jurkat, HeLa, Mouse brain
Cellular Localization:
Cytoplasm.
Calculated MW:
22kDa
Observed MW:
22kDa
Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein (PubMed:34362892). Confers NAADP sensitivity to the two pore channel complex (TPCs) by acting as TPC accessory protein necessary for NAADP-evoked Ca(2+) release (PubMed:34362892). ( LSM12_HUMAN,Q3MHD2 )
Purification Method
Affinity purification
Gene ID
124801
RRID
AB_2763382
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LSM12 Rabbit pAb (CAB15947) at 1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
