The LSM3 Antibody (CAB13189) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and is highly specific to LSM3 in human samples, making it ideal for Western blot applications. By targeting LSM3, this antibody allows for the detection and analysis of LSM3 protein levels in various cell types, providing insight into its role in gene expression regulation.LSM3 is a key player in mRNA decay pathways and is essential for maintaining proper RNA stability and turnover. Dysregulation of LSM3 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
LSM3 Antibody
SKU:
CAB13189
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SMX4, USS2, YLR438C, LSM3
Positive Sample:
Mouse brain, Mouse kidney
Cellular Localization:
Nucleus.
Calculated MW:
12kDa
Observed MW:
12kDa
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
Purification Method
Affinity purification
Gene ID
27258
RRID
AB_2760040
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LSM3 Rabbit pAb (CAB13189) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
