Anti-LY86 Antibody (CAB6185)
- SKU:
- CAB6185
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-LY86 Antibody |
| Antibody SKU: | CAB6185 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-162 of human LY86 (NP_004262.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse liver, Mouse stomach |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-162 of human LY86 (NP_004262.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GGGG KAWP THVV CSDS GLEV LYQS CDPL QDFG FSVE KCSK QLKS NINI RFGI ILRE DIKE LFLD LALM SQGS SVLN FSYP ICEA ALPK FSFC GRRK GEQI YYAG PVNN PEFT IPQG EYQV LLEL YTEK RSTV ACAN ATIM CS |
| Gene ID: | 9450 |
| Uniprot: | O95711 |
| Cellular Location: | Secreted, extracellular space |
| Calculated MW: | 17kDa |
| Observed MW: | 24kDa |
| Synonyms: | LY86, MD-1, MD1, MMD-1, dJ80N2.1 |
| Background: |
| UniProt Protein Function: | LY86: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Apoptosis Chromosomal Location of Human Ortholog: 6p25.1 Cellular Component: plasma membrane Biological Process: apoptosis; cell proliferation; humoral immune response; positive regulation of lipopolysaccharide-mediated signaling pathway |
| UniProt Code: | O95711 |
| NCBI GenInfo Identifier: | 20138465 |
| NCBI Gene ID: | 9450 |
| NCBI Accession: | O95711.1 |
| UniProt Secondary Accession: | O95711,Q9UQC4, |
| UniProt Related Accession: | O95711 |
| Molecular Weight: | 17,906 Da |
| NCBI Full Name: | Lymphocyte antigen 86 |
| NCBI Synonym Full Names: | lymphocyte antigen 86 |
| NCBI Official Symbol: | LY86Â Â |
| NCBI Official Synonym Symbols: | MD1; MD-1; MMD-1; dJ80N2.1Â Â |
| NCBI Protein Information: | lymphocyte antigen 86 |
| UniProt Protein Name: | Lymphocyte antigen 86 |
| UniProt Synonym Protein Names: | Protein MD-1 |
| Protein Family: | Lymphocyte antigen |
| UniProt Gene Name: | LY86Â Â |
| UniProt Entry Name: | LY86_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LY86 antibody (CAB6185) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using LY86 antibody (CAB6185) at dilution of 1:200 (40x lens). |
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