Description
Mouse CCL2/MCP-1 Recombinant Protein (C-His)
Mouse CCL2/MCP-1 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Gln24-Asn148, with a C-terminal His tag. Predicted molecular weight: 16.75 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. C-C motif chemokine 2 (CCL2/MCP-1) is a ~16 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. For research use only.
Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. Plays an important role in mediating peripheral nerve injury-induced neuropathic pain. Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B.
| Product Name: | Mouse CCL2/MCP-1 Recombinant Protein (C-His) |
| SKU: | GXRP06128 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Platelet-derived growth factor-inducible protein JE, Small-inducible cytokine A2, Ccl2, Je, Mcp1, Scya2 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Gln24-Asn148 |
| Calculated MW: | 16.75 kDa |
| UniProt: | P10148 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
