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FITC Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0129)

Datasheet MSDS
SKU AGEL0129
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone A7R34
Conjugation FITC
Applications FC
€82 - €200

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 Monoclonal Antibody (FITC-conjugated) A7R34 (AGEL0129) is a powerful tool for researchers investigating the CD127 protein, a key marker for identifying and studying specific immune cell populations. This monoclonal antibody, derived from mouse hybridoma cells, is optimized for flow cytometry applications, offering high specificity and sensitivity in detecting CD127 expression in mouse samples.CD127, also known as interleukin-7 receptor alpha chain, is essential for the development and function of T cells, particularly memory T cells and regulatory T cells. By targeting CD127, researchers can gain insights into the immune system's response to various stimuli and its role in diseases such as autoimmune disorders, infectious diseases, and cancer.

The FITC conjugation of this antibody allows for easy visualization and analysis of CD127-expressing cells, aiding in phenotypic characterization and functional studies.With the Mouse CD127 Monoclonal Antibody (FITC-conjugated) A7R34 (AGEL0129), researchers can delve deeper into the complexities of immune cell populations and their interactions, paving the way for advancements in immunology research and potential therapeutic strategies targeting CD127-related pathways.

Product Title:FITC Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0129
Size:50 Tests, 100 Tests, 200 Tests
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
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