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Key Features

Biotin Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0128)

Datasheet MSDS
SKU AGEL0128
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone A7R34
Conjugation Biotin
Applications FC
€60 - €135

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Description

system_update_altDatasheetsystem_update_altMSDS

Biotin Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 Monoclonal Antibody (Biotin Conjugated, A7R34) is a powerful tool for researchers investigating the CD127 protein, also known as the IL-7 receptor alpha chain. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, is specifically designed for use in various immunoassays and flow cytometry applications.CD127 is a crucial component of the interleukin-7 receptor complex, playing a pivotal role in the development and function of immune cells, particularly T cells. By targeting CD127, researchers can explore the regulation of T cell homeostasis, proliferation, and survival, shedding light on immune responses in health and disease.

With its high specificity and sensitivity, the Mouse CD127 Monoclonal Antibody (Biotin Conjugated, A7R34) is a valuable tool for studies in immunology, oncology, and autoimmune diseases. By enabling precise detection and analysis of CD127 expression in various cell populations, this antibody facilitates in-depth investigations into immune system dynamics and potential therapeutic interventions.

Product Title:Biotin Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0128
Size:25µg, 100µg
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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