Biotin Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0128)
- SKU:
- AGEL0128
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- A7R34
- Conjugation:
- Biotin
- Applications:
- FC
Frequently bought together:
Description
Product Title: | Biotin Anti-Mouse CD127/IL-7RA Antibody [A7R34] |
SKU: | AGEL0128 |
Size: | 25µg, 100µg |
Clone No: | A7R34 |
Synonyms: | Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127; |
Host Species: | Rat |
Reactivity: | Mouse |
Application: | FCM |
Isotype: | Rat IgG2a, κ |
Isotype Control: | Biotin Rat IgG2a, κ Isotype Control[2A3] |
Form: | Liquid |
Conjugation: | Biotin |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Swissprot: | P16872 |
Gene ID: | 16197 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |