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FITC Anti-Mouse CD206 Antibody [C068C2] (AGEL1651)

Datasheet MSDS
SKU AGEL1651
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Applications FC
$149 - $314

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Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Mouse CD206 Antibody [C068C2]

The Mouse CD206 Monoclonal Antibody (FITC Conjugated) is a cutting-edge tool for researchers studying CD206, a cell surface receptor involved in immune responses and inflammation. This monoclonal antibody, produced through advanced technology, specifically targets the CD206 protein in mouse samples and is optimized for use in flow cytometry and fluorescence microscopy applications.CD206, also known as mannose receptor, is a key player in the immune system, regulating inflammation and participating in antigen presentation. Its involvement in recognizing and binding glycoproteins makes it a crucial molecule in immune response pathways.

Researchers studying infectious diseases, autoimmune disorders, and inflammation-related conditions will benefit from the precise detection and analysis that this antibody provides.By utilizing the Mouse CD206 Monoclonal Antibody (FITC Conjugated), scientists can gain valuable insights into the role of CD206 in various biological processes, paving the way for innovative therapeutic approaches and targeted interventions. This high-quality antibody offers reliable performance and accurate results, making it an indispensable tool for immunology, microbiology, and pharmacology research.

Product Title:FITC Anti-Mouse CD206 Antibody [C068C2]
SKU:AGEL1651
Size:50 Tests, 100 Tests, 200 Tests
Clone No:C068C2
Synonyms:MMR;MR;MRC1;macrophage mannose receptor;mannose receptor ;
Host Species:Rat
Reactivity:Mouse
Application:FCM;ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q61830
Gene ID:17533
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
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