Mouse CD80 Monoclonal Antibody (APC Conjugated) [16-10A1](AGEL0534)

SKU:
AGEL0534
€262

Description

Overview:

Title:Mouse CD80 Monoclonal Antibody (APC Conjugated)
Host Species:Armenian Hamster
Size:100 ?g
Volume Per Test:1mg/mL

Background:

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Antibody Information:

Isotype:IgG2a,k
GeneID:12519
SwissProt:Q00609
Synonyms:T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7
Clone:16-10A1
Conjugation:APC

Applications:

Reactivity:Mouse
Tested Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ? 2.0 µg per 10e6 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2˜8°C and protected from prolonged exposure to light. Do not freeze.

Antibody Image:

Mouse CD19 Monoclonal Antibody (FITC Conjugated)C57BL/6 murine splenocytes are stained with Anti-Mouse CD80 Monoclonal Antibody(APC Conjugated)[Used at ?g/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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Additional Information

Product type:
Antibody
Application:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
16-10A1
Conjugation:
APC
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