Description
Mouse CD8B Recombinant Protein (N-His)
Mouse CD8B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu22-Thr134, with an N-terminal His tag. Predicted molecular weight: 15.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. T-cell surface glycoprotein CD8 beta chain is a ~24 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. For research use only.
In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
| Product Name: | Mouse CD8B Recombinant Protein (N-His) |
| SKU: | GXRP14083 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | CD8b, Cd8b, Cd8b1, Ly-3, Lymphocyte antigen 3, Lyt-3, Lyt3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu22-Thr134 |
| Calculated MW: | 15.12 kDa |
| UniProt: | P10300 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
