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Mouse DCC Recombinant Protein (N-His)
Key Features

Mouse DCC Recombinant Protein (N-His) (GXRP05955)

SKU GXRP05955
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse DCC Recombinant Protein (N-His)

Mouse DCC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser39-Ser232, with an N-terminal His tag. Predicted molecular weight: 23.31 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Netrin receptor DCC is a ~158 kDa protein. Receptor for netrin required for axon guidance. For research use only.

Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

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