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Mouse FLT1 Recombinant Protein (C-His)
Key Features

Mouse FLT1 Recombinant Protein (C-His) (GXRP09073)

SKU GXRP09073
Product Type Recombinant Protein
Species Mouse
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Mouse FLT1 Recombinant Protein (C-His)

Mouse FLT1 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Tyr23-Glu759, with a C-terminal His tag. Predicted molecular weight: 85.65 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Vascular endothelial growth factor receptor 1 is a ~149 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. For research use only.

Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific.

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