Description
Mouse GPC1 Recombinant Protein (C-His)
Mouse GPC1 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Asp24-Ser529, with a C-terminal His tag. Predicted molecular weight: 58.57 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Glypican-1 is a ~61 kDa protein. Cell surface proteoglycan that bears heparan sulfate. For research use only.
Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Binds Cu(2+) or Zn(2+) ions.
| Product Name: | Mouse GPC1 Recombinant Protein (C-His) |
| SKU: | GXRP12493 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | GPC1, Glypican-1, Secreted glypican-1 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Asp24-Ser529 |
| Calculated MW: | 58.57 kDa |
| UniProt: | Q9QZF2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
