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PE Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL1105)

Datasheet MSDS
SKU AGEL1105
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone M1/70
Conjugation PE
€38 - €128

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Description

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PE Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (PE-conjugated, M1/70) is a versatile tool for researchers studying immune cell populations expressing CD11b, a well-known marker of myeloid cells. This antibody, conjugated to the fluorochrome phycoerythrin (PE), offers reliable detection and analysis of CD11b-expressing cells in flow cytometry applications.CD11b, also known as integrin alpha M, is a key adhesion molecule involved in various immune responses, including cell adhesion, migration, and phagocytosis. Its expression on myeloid cells, such as monocytes, macrophages, and granulocytes, makes it a valuable indicator for studying immune cell activation and differentiation.

The monoclonal antibody M1/70 specifically recognizes CD11b in both mouse and human samples, allowing researchers to compare and analyze immune cell populations across species. Its PE conjugation enables easy detection of CD11b-positive cells in flow cytometry experiments, providing valuable insights into the role of myeloid cells in immune responses, inflammation, and disease pathology.Whether investigating the immune response to infection, inflammation, or cancer, the Mouse/Human CD11b Monoclonal Antibody (PE-conjugated, M1/70) is a reliable tool for researchers seeking to characterize and quantify CD11b-expressing cells in diverse biological samples.

Product Title:PE Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL1105
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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