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PE/Cyanine5 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0310)

Datasheet MSDS
SKU AGEL0310
Product Type Antibody
Antibody Type Monoclonal Antibody
Host Species Rat
Isotype IgG2b
Clone M1/70
Conjugation PE/Cy5
Applications FC
€40 - €108

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine5 Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (PE-Cy5 Conjugated, M1/70) from Assay Genie (AGEL0310) is a powerful tool for researchers studying immune cells and inflammation. This antibody is specifically designed to target CD11b, a key cell surface marker involved in immune responses.CD11b, also known as integrin alpha-M, is primarily expressed on the surface of macrophages, monocytes, and neutrophils. It plays a crucial role in cell adhesion, migration, and phagocytosis, making it an important player in the innate immune system. By targeting CD11b, researchers can identify and analyze these immune cells in various tissues and experimental models.

This monoclonal antibody is conjugated with PE-Cy5, a fluorescent dye that allows for easy detection and visualization of CD11b-positive cells. Its specificity for both mouse and human samples makes it versatile for a wide range of research applications, including flow cytometry, immunofluorescence, and cell sorting.Whether investigating inflammatory responses, immune cell activation, or immune cell populations in different tissues, the Mouse/Human CD11b Monoclonal Antibody (PE-Cy5 Conjugated, M1/70) provides reliable results and valuable insights for immunology and disease-related studies.

Product Title:PE/Cyanine5 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0310
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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