Description
Mouse S100A8 Recombinant Protein (N-His-SUMO)
Mouse S100A8 Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Pro2-Glu89, with an N-terminal His-SUMO tag. Predicted molecular weight: 22.50 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein S100-A8 (S100A8) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. For research use only.
It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69.
| Product Name: | Mouse S100A8 Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP05859 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Caga, S100 calcium-binding protein A8, Protein S100-A8, Calgranulin-A, Mrp8, Chemotactic cytokine CP-10, p8, Leukocyte L1 complex light chain, S100a8, Migration inhibitory factor-related protein 8, Pro-inflammatory S100 cytokine, MRP-8 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Pro2-Glu89 |
| Calculated MW: | 22.50 kDa |
| UniProt: | P27005 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |