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Mouse TRMT112 Recombinant Protein (C-Strep)
Key Features

Mouse TRMT112 Recombinant Protein (C-Strep) (GXRP13956)

SKU GXRP13956
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag C-Strep
$458 - $2,412

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Description

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Mouse TRMT112 Recombinant Protein (C-Strep)

Mouse TRMT112 Recombinant Protein (C-Strep) is a recombinant protein expressed in E. coli, spanning Met1-Thr125, with a C-terminal Strep tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Multifunctional methyltransferase subunit TRM112-like protein is a ~14 kDa protein. Acts as an activator of both rRNA/tRNA and protein methyltransferases. For research use only.

Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Together with methyltransferase THUMPD3, catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates and at position 7 of tRNA(Trp).

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