The MSMB Monoclonal Antibody (CAB4168) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit monoclonal sources, exhibits high reactivity and specificity towards human samples, making it an ideal choice for a variety of experimental applications, including immunohistochemistry and Western blotting.MSMB, also known as beta-microseminoprotein, is a promising biomarker for prostate cancer due to its altered expression levels in malignant prostate tissues. By targeting the MSMB protein, researchers can investigate its role in prostate cancer biology, potentially leading to new diagnostic and therapeutic strategies for this prevalent disease.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
MSMB Monoclonal Antibody
SKU:
CAB4168
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0912
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene.
Purification Method
Affinity purification
Gene ID
4477
RRID
AB_2863200
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MSMB Rabbit mAb (CAB4168) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Immunofluorescence analysis of U-2 OS cells using MSMB Rabbit mAb (CAB4168) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
