The NAT1 Antibody (CAB1563) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbit host species, shows high specificity for human samples and is validated for use in various applications, including Western blotting.N-acetyltransferase 1 (NAT1) is known for its role in the metabolism of a wide range of drugs, carcinogens, and environmental toxins. Variations in NAT1 expression and activity have been linked to drug toxicity, cancer susceptibility, and other health conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
NAT1 Antibody
SKU:
CAB1563
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AAC1, MNAT, NATI, NAT-1, NAT1
Positive Sample:
U-937
Cellular Localization:
Cytoplasm.
Calculated MW:
34kDa
Observed MW:
33kDa
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
9
RRID
AB_2763037
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from U-937 cells, using NAT1 Rabbit pAb (CAB1563) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
