Description
Nivolumab ELISA Kit
The Nivolumab ELISA Kit (SKU: GXEL00212) is a quantitative sandwich ELISA designed for the accurate quantitative detection of Nivolumab across Plasma, Serum. With a working range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml, the kit combines a simple protocol with dependable colorimetric read-out for confident quantification.
Nivolumab is a human immunoglobulin G4 (IgG4) monoclonal antibody that binds to the programmed cell death 1 (PD-1) receptor and selectively blocks interaction with its programmed death ligands PD-L1 and PD-L2. Upregulation of PD-1 ligands occurs in some tumors and signalling through this pathway can contribute to inhibition of active T-cell immune surveillance of tumour tissue. The inhibitory effect of PD-1 and its ligands occurs through the promotion of apoptosis in antigen specific T cells while simultaneously blocking apoptosis in suppressor T cells. Blocking PD-1 activity has been shown to lead to decreased tumour growth in mouse tumour models.
Backed by Assay Genie quality control and technical support, this Nivolumab ELISA Kit is an ideal tool for laboratories studying Nivolumab. Order the Nivolumab ELISA Kit from Assay Genie for dependable performance.
| Product Name: | Nivolumab ELISA Kit |
| SKU: | GXEL00212 |
| Accession: | Q15116 |
| Alternative Names: | BMS-936558, MDX-1106, ONO-4538, 946414-94-4 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 0.156 μg/ml |
| Range: | 0.31-5 μg/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 0.156 μg/ml |
| Detection Range | 0.31-5 μg/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 20% prior to the expiration date under appropriate storage condition.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
