The NLRP5 Antibody (CAB9886) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to NLRP5, this antibody enables the detection and analysis of the protein in various cell types, offering valuable insights for studies in immunology and autoinflammatory diseases.NLRP5, also known as NLR family pyrin domain containing 5, is essential for the activation of the NLRP3 inflammasome and the subsequent release of pro-inflammatory cytokines.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NLRP5 Antibody
SKU:
CAB9886
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MATER, NALP5, PAN11, PYPAF8, CLR19.8, NLRP5
Positive Sample:
SKOV3
Cellular Localization:
Cytoplasm, Mitochondrion, Nucleus, Nucleolus.
Calculated MW:
134kDa
Observed MW:
134kDa
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.
Purification Method
Affinity purification
Gene ID
126206
RRID
AB_2770601
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from SKOV3 cells, using NLRP5 Rabbit pAb (CAB9886) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 20S.
