The NOSTRIN Antibody (CAB15938) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is specifically designed for detection and analysis of NOStR1 in human samples, making it ideal for studies in oxidative stress, inflammation, and cardiovascular disease.NOStR1, also known as NOSTRIN (Nitric Oxide Synthase Traffic Inducer), plays a crucial role in NOX enzyme regulation and ROS signaling pathways, which are important in various physiological and pathological processes. By targeting NOStR1, researchers can explore its function in oxidative stress responses, cellular signaling, and disease progression, providing insights into potential therapeutic targets for conditions associated with ROS dysregulation.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NOSTRIN Antibody
SKU:
CAB15938
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
Purification Method
Affinity purification
Gene ID
115677
RRID
AB_2763372
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NOSTRIN Rabbit pAb (CAB15938) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Immunofluorescence analysis of U-2 OS cells using NOSTRIN Rabbit pAb (CAB15938) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
